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Swallowed like any supplement

Attend all scheduled appointments and don't hesitate to contact your GP or diabetes nurse between visits if you experience: Severe or persistent nausea/vomiting preventing adequate nutrition or hydration Signs of pancreatitis (severe, persistent abdominal pain radiating to the back) Symptoms of gallbladder problems (right upper abdominal pain, particularly after eating) Unexplained visual changes Signs of hypoglycaemia if taking other diabetes medications Realistic goal-setting improves long-term success

10.1146/annurev-med-051022-043645 Annu Rev Med

IUDs and implants deliver hormones directly into the body, bypassing the GI tract entirely, making them the safest hormonal options during Retatrutide treatment

Higher concentration means lower units per dose (easier to dose small amounts precisely)