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Although AMPA/kainate receptor levels remain relatively constant or increase with age, the impaired ability for neurons to form new synaptic contacts with OPCs, combined with a decline in NMDA receptors, may decrease OPC differentiation and activity-dependent myelination in the aged brain (Spitzer et al., 2019
Moreover, the role of endogenous glucagon-like peptide 1 (GLP-1) in the body is reviewed, including neuronally synthesized GLP-1, with a focus on how recent research developments may point towards therapeutic utility of GLP-1RAs in neuro-ophthalmology
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GLP-1 receptor agonists influence metabolism through three primary pathways: appetite modulation, glucose-dependent insulin secretion, and slowed gastric emptying
By sixty, that number drops to 80 nanograms per milliliter
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