The maintenance phase sustains them
The First Three Years of Screening for Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) by Newborn Screening Ontario. BMC Pediatrics , vol
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In the STEP 1 extension, people who stopped semaglutide regained 11.6 percentage points of body weight over 52 weeks, ending with an average net loss of 5.6% from baseline while lifestyle support continued (STEP 1 extension data)
Clinicians should systematically evaluate these potential causes when patients report persistent fatigue during GLP-1 therapy, as many are modifiable through dietary counseling, hydration strategies, or medication adjustment