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Schematic diagram of the experimental procedure for cocaine-induced CPP in rats Figure 6
Gradual taper reduces rebound effects
Principal componentbased epigenetic clocks (PCHorvath1, PCHorvath2, PCHannum, PCPhenoAge, PCGrimAge) were calculated using the PC-Clocks repository ( Non-PC Horvath, Hannum, and DNAmPhenoAge clocks were calculated using the methyAge function in the ENmix R package (v1.44.3)
Tirzepatide and semaglutide represent two distinct approaches to GLP-1 therapy: tirzepatide activates both GLP-1 and GIP receptors, while semaglutide targets only the GLP-1 pathway
It has attracted significant, sustained attention in in-vitro research focused intensely on connective tissue, skeletal muscle fibers, tendons, ligaments, and highly specialized gastrointestinal tissue models
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