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Improves survival under oxidative stress by increasing nitric oxide (NO) expression, thereby protecting the endothelial lining of the blood vessels from oxidative damage
These studies revealed overall structural similarity of KARs with other iGluRs, particularly AMPA receptors in the closed and activated states, and the agonist-bound non-conducting state adopting a conformation which is different from other iGluRs
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Free radical damage contributes to aging and disease
has served on advisory boards for Wilson Therapeutics, Vivet Therapeutics and GMP-Orphan SAS and has received speaker fees from EVER Pharma, Boehringer Ingelheim and Nutricia
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