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It works by mimicking a hormone in your body called GLP-1, which helps regulate your appetite and food intake

Journal of inherited metabolic disease

Constipation is less dose-dependent and can persist, making it a more durable reason for discontinuation in patient reports. Sulfur burps reflect food sitting longer in a slowed stomach. Fatigue ranks second only to nausea in patient forums, although much of it tracks the calorie deficit rather than tirzepatide itself. Fried or fatty foods, coffee, meat, and alcohol can also become less appealing

It also is necessary for red blood cell production

These findings are somewhat misleading and not all that applicable to human longevity