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Werner, M
These observations are in line with the previous findings of Dixon et al
In principle, a hyperoxidizing ER might simply blunt the UPR rather than improve ER function, since activation of at least the UPR sensors ATF6 and IRE1 can be inhibited by oxidation (Nadanaka, Okada, Yoshida, & Mori, 2007
Recent advances in parasite biology suggest a compartmentalization of redox metabolism [5] as well as of cellular processes that are sites of drug action [6]
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