Within this context, it is not surprising that a great deal of inhibitors and pro-drugs targeting GSTs have been synthesized and tested so far, with new scaffolds or analogues being reported every year
Glutathione is also a precursor of many detoxifying enzymes, including glutathione peroxidase, responsible for neutralizing waste products from cellular respiration or the process of 'cell death' (apoptosis) (5)
Yang Y, Wang Y, Guo L, Gao W, Tang T, Yan M
In the case of methylcobalamin, significant electronic density is transferred from the glutathione monoanion to it during the CASSCF(14,13) calculation, until it reaches 1 e at the end of the reaction
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