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Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress

For studies with a calorie-restricted and body-weight-loss-matched control group, HFHS diet (58 kcal% fat, D12331i, Research Diets) was weighed and provided as one separate pellet per mouse at the time of injection

N-acetylcysteine is a supplement form of cysteine, one of the three essential amino acids that constitute glutathione

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Rising regulatory approvals, reimbursement rates, and awareness of weight-loss drugs are expected to contribute to their increasing use across the world