[19] [21] The compounds targeted in this manner by GSTs encompass a diverse range of environmental or otherwise exogenous toxins, including chemotherapeutic agents and other drugs, pesticides, herbicides, carcinogens, and variably-derived epoxides
GLP-1 receptor agonist medications like semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro) work by mimicking this natural hormone, though at higher and more sustained levels than the body would produce on its own
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Additionally, by acting on receptors in the brain, it can help reduce food cravings and improve eating behaviors
In the rodent studies, this overgrowth (hyperplasia) eventually led to medullary thyroid tumours