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Such a condition is centered on the removal of inhibition of the carnitine handling enzyme CPT1 via the specific down-regulation of acetyl-CoA carboxylase 2 (ACC2), with a strong reduction of the malonyl-CoA pool responsible for CPT1 inhibition (Koundouros and Poulogiannis, 2020)
But, as ever with nutrition, its not a one-size-fits-all approach
Based on this research, docking was performed on the dual copper-binding sites of mTYR and hTYR
To understand oxidative stress and its effects, we need to dive into the science
doi: 10.1177/1084713812447737
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