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3.1.9 Epigallocatechin-3-gallate (EGCG) and epicatechin EGCG, a polyphenol abundant in green tea extract, is a STAT1 inhibitor.EGCG prevents cisplatin cytotoxicity through anti-apoptotic and antioxidant effects ( in vitro and ex vivo (Xie et al., 2004).EGCG acts through phosphatidylinositol 3-kinase (PI3K)/Akt signalling in cochlear NSCs to promote cell growth and neuronal differentiation, which can be used for the treatment of hearing loss (Zhang et al., 2016), and has an important protective mechanism against cochlear oxidative damage
Anal Biochem 529:127143 Aoyama K, Nakaki T (2013) Neuroprotective properties of the excitatory amino acid carrier 1 (EAAC1)
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The J-code for the drug must still accompany it on the claim
Its anti-inflammatory and antioxidant properties might help soothe the skin and reduce inflammation due to skin conditions such as acne, eczema, and rosacea 1,7
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