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Lastly, glutathione production is directly linked to the amount of cysteine available in cells

This distinction is critical, as the field encompasses both specific enzymatic modifications and non-enzymatic chemical alterations that can occur under certain metabolic deficiencies or, more problematically, as technical artifacts during experimental procedures

Initially developed in the 1960s as a mucolytic agent (1), NAC was later identified as an effective antidote for acetaminophen toxicity by detoxifying N-acetyl-p-benzoquinone imine (NAPQI) (2) (Figure 1)

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Chandrasekaran, A