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By inhibiting oxidative phosphorylation (OXPHOS), which induces mitochondrial hyperpolarization and subsequently stimulates ROS production [23], the oxidation of palmitoylcarnitine (C16-carnitine) produces more ROS in mitochondria than carbohydrates [24]

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However, the large number of significant correlations noted in this study between Parasutterella relative abundance and EWAT metabolites strongly supports the relevance of this genus to the EWAT metabolome

Beran M, Kantarjian H, O'Brien S, Estey E, Andreeff M , Pierce S, Robinson J, Koller C, Keating M