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The etiologies of five congenital hypothyroid patients were unknown because these patients did not show positive test results for thyroid radionuclide uptake, thyroid sonography, or serum thyroglobulin, although they were kept on regular LT 4 therapy

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ALCA, together with alpha-lipoic acid, was shown to improve mitochondrial energy metabolism and decrease oxidative stress leading to improved memory in aged rats [144, 145]