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Permeability assays To establish the co-culture BBB model brain PCs were passaged at P11 (7 10 3 cells/insert) to the bottom (brain) side of culture inserts (polyester membrane

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Metformin affects gut microbiota composition and diversity associated with amelioration of dextran sulfate sodium-induced colitis in mice

Current Research and Future Trends Expanding Clinical Applications Ongoing studies are exploring the role of AOD-9604 in treating metabolic conditions such as: Type 2 diabetes Insulin resistance Non-alcoholic fatty liver disease (NAFLD) Up to 95% of individuals with type 2 diabetes also present with NAFLD, emphasizing the need for multi-functional metabolic therapies Joint Health & Cartilage Regeneration In addition to fat metabolism, AOD-9604 may stimulate cartilage repair and support joint health