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In short, despite some heterogeneity across the trials, GLP-1 receptor agonists were shown to reduce the hazard ratios [95%CI] for 3-MACE by 12 [618]%, cardiovascular death by 12 [419]%, myocardial infarction by 9 [016]% and stroke by 16 {724]%
(PubMed) Stamp LK, O'Donnell JL, Frampton C, Drake JM, Zhang M, Chapman PT
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demonstrated cumulative effects after multiple CJC-1295 DAC doses, with IGF-1 remaining above baseline for up to 28 days (PMID: 16352683)
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