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Hsu, and J.-H
no safety data supports continuous use beyond 12 weeks
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However, long-term human data is limited, which is why medical assessment and monitoring are essential
Skin Aging Claims Versus Systemic Anti-Aging Claims Skin aging claims can point to topical studies on photoaging and wrinkle parameters, but systemic anti-aging claims often rely on gene expression, oxidative stress, inflammation, or animal data [2], [10], 17
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