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Studies looking at NR doses up to 2,000mg per day and NMN doses up to 1,200mg per day found no differences in adverse effects between intervention and placebo groups.31 4 In studies of higher doses that produced adverse effects, typical reactions included:32 Headache Dry mouth GI upset Muscle cramps or spasms As with many forms of vitamin B, NR can cause some flushing, and both NR and NMN can cause digestive upset
no overcommitting
The edema usually does not require hospitalization unless there is coexisting congestive heart failure
There's really no data either way on this issue of GLP-1s affecting the efficacy of minimally invasive skin-tightening devices, he notes
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