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Whilst injections bypass gut absorption, conditions like active Crohn's disease or coeliac disease may cause increased metabolic demands that could influence how quickly B12 is utilised
What that means in real life: The peptide stays active long enough for consistent absorption
Recent studies have shown that C16-carnitine induces mitochondrial dysfunction and leads to calcium overload by increasing mitochondrial fission in SH-SY5Y cells
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Wild-type IDH1 overexpression fully rescued the phenotype, demonstrating that the observations are not due to off-target effects (Extended Data Fig
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