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Its phase 2 results were published in The Lancet and presented at ObesityWeek 2025, and Eli Lilly stated phase 3 enrolment was planned to begin by the end of 2025
How it works: MOTS-C is a naturally occurring mitochondrial peptide discovered at USC in 2015
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While this change does not equate to full FDA approval, it reduces a key barrier that has constrained compounding pharmacies
Preservation of Lean Muscle Mass : Unlike many metabolic interventions that induce general weight loss, 5-Amino-1MQ studies report a preservation of lean muscle mass during adipose reduction
