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Individuals with digestive conditions such as Crohns disease, celiac disease, or those whove undergone certain procedures affecting the stomach or small intestine may struggle with absorption
Diagnosis typically includes testing for anti-intrinsic factor antibodies (and sometimes anti-parietal cell antibodies)
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The largest Phase 2b trial used 0.25, 0.5, and 1 mg per day for 24 weeks, but it missed its main weight-loss endpoint
