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Common side effects include nausea (affecting 20-40% of patients, particularly during dose initiation), constipation, diarrhea or loose stools, abdominal discomfort or cramping, decreased appetite beyond desired levels, fatigue or reduced energy, and headaches
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment
10.1016/j.cmet.2005.02.005 56 GaschlerM
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RGD-coated MBs specifically targeted inflamed endothelium, enhancing the delivery of both pHPMA and ribavirin across the BBB
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