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For GLP-1 RAs, projected QALY gain was 36,090 at a total healthcare cost increment of AU$2.9 billion, resulting in an ICER of AU$79,742 per QALY gained

In another trial, very high-dose vitamin D supplementation (50,000 IU/week for 24 weeks) had no effect on physical performance in elderly individuals with heart failure

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This means Canadian patients likely will not have access to prescription Retatrutide through standard healthcare channels until 2027 or 2028