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The pathological characteristic of atherosclerosis is the formation of pathological plaques containing endothelial cells (ECs), macrophages, and vascular smooth muscle cells (VSMCs)

Collectively, spermidine acts through endothelial protection, oxidative stress reduction, mitochondrial support, and MAP1S-driven autophagy to prevent or even reverse liver fibrosis 121,122

Shifting by four or five days disrupts the steady state and may increase breakthrough symptoms between doses

Following a single adenine (A) base addition, adapters with a corresponding, complementary thymine (T) overhang were ligated to the cDNA fragments