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After medication-assisted reproduction treatments
doi: 10.3390/nu13051404 33
IL-6/JAK/STAT signaling delivered via spatial proximity from CAFs to tumor cells functionally promoted EMT, invasion, and chemoresistance
However, despite previous reports on the potential advantage posed by GLP1-based multi-agonists in the management of obesity and metabolic disease, as recently exemplified by the dramatic body weight-lowering actions of the GLP1/GIP dual agonist, tirzepatide 47 , to our knowledge, no study has addressed to date the pharmacological characterization of GLP1-based unimolecular multi-agonists for management of reproductive and metabolic alterations of PCOS, using suitable preclinical models, as pre-requisite for their application in clinics
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This cold temperature slows down the natural degradation process
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