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Vitamin B12 is water-soluble, meaning excess amounts are usually excreted by the body

Cagrilintide monotherapy uses up to 4.5 mg weekly, while retatrutide reaches 12 mg weekly, but combining these maximum doses would almost certainly be unsafe

Maintenance dosing schedules: Weekly injections for the first few months Bi-weekly or monthly injections after that Adjusting Frequency Based on Clinical Response The B12 injection schedule might need to change based on how well the treatment works

Behavioral tests included developmental milestones, olfactory discrimination, negative geotaxis, open field, and three-chamber social interaction