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These effects are often dose-dependent and may decrease over time as the body adjusts to the treatment

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Glutathione works with Vitamin C, another antioxidant, helping to restore it to its active form after it has done its job

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A recent regulatory example, accepted by the US EPA, of a non-animal risk assessment for the fungicide chlorothalonil in an occupational scenario combined in vitro PoDs from MucilAir readouts (i.e., TEER, lactate dehydrogenase leakage and resazurin metabolism analyses) with dosimetry information obtained from a computational fluid-particle dynamics (CFPD) model (Corley et al., 2021