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Combined with the molecular weight argument (semaglutide is too large to easily cross biological barriers into milk) and the poor oral bioavailability (any swallowed semaglutide would be destroyed in the infant gut), the safety profile looks reassuring
doi: 10.1210/jcem.77.6.7903313 93 SinhaDKBalasubramanianATatemAJRivera-MirabalJYuJKovacJet al
Who is Semaglutide Treatment Right For Semaglutide treatment is suitable for a variety of individuals, but it is particularly beneficial for: Individuals with Type 2 Diabetes If you have type 2 diabetes and struggle to manage your blood sugar levels with diet, exercise, and other medications, Semaglutide could be a valuable addition to your treatment plan
A randomized controlled trial is currently underway evaluating prophylactic metformin for patients starting clozapine (Siskind D et al, BMJ Open 2018;8(3):e021000)
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