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The review also highlights the role of fiber and probiotics in improving bowel regularity and easing gastrointestinal side effects, along with thermogenics like caffeine or green tea, which may help increase energy

History of pancreatitis Severe gastrointestinal disease Gallbladder disease or a history of cholelithiasis Pregnancy or breastfeeding Concomitant use of insulin or insulin secretagogues (e.g., sulphonylureas), which may increase hypoglycaemia risk Retatrutide, like other incretin-class medicines, may slow gastric emptying, which can affect the absorption of oral medicines taken at the same time

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The homogenized samples were then centrifuged at 4C for 10 minutes at 1500 g