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The American Academy of Family Physicians and NIH identify the following clinical manifestations: Fatigue and generalized weakness Megaloblastic anemia (abnormally large, immature red blood cells) Tingling or numbness in the hands and feet (peripheral neuropathy) Difficulty walking and balance problems Cognitive disturbances including memory difficulty and confusion Mood changes, including depression and irritability Glossitis (swollen, inflamed tongue) Early symptoms such as fatigue and mild tingling are often attributed to stress, aging, or other conditions
Related lab tests: Hemoglobin A1C, Glucose, Comprehensive Metabolic Panel, Kidney Profile, Lipid Panel, Lipase, Amylase, Hepatic Function Panel with GGT, CBC, Ferritin, Iron and TIBC, Vitamin B12, Folate, and Vitamin D
The systematic review of various evidence and studies suggests that a higher dietary intake of B vitamins could lower the risk of advanced macular degeneration
Best suited for immune and antioxidant support
Drug/Laboratory Test Interactions: Persons taking most antibiotics, methotrexate and pyrimethamine invalidate folic acid and vitamin B 12 diagnostic blood assays
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