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TDP-43 stabilises the processing intermediates of mitochondrial transcripts
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Once daily administration produced statistically significant placebo-corrected reductions in supine and standing blood pressures at 24 hours postdose, averaging about 12/6 mmHg in the standing position and 13/7 mmHg in the supine position in patients with mild to moderate hypertension
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In preclinical models , this activity is associated with improved structural integrity and skin-related research outcomes
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