tirzepatide fda approved Approves Diabetes Drug for Chronic Weight Management Eli Lilly targets FDA approval

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TIRZEPATIDE OVERVIEW Category: Dual GIP and GLP-1 Receptor Agonist How It Works: Tirzepatide selectively activates both the GIP (Glucose-dependent Insulinotropic Polypeptide) and GLP-1 (Glucagon-like Peptide 1) receptors, a dual agonism that provides synergistic benefits

One small study (Nauck et al., Diabetes, Obesity and Metabolism , 2016) compared once-weekly semaglutide to twice-weekly half-doses and found no difference in efficacy but slightly lower nausea rates in the split-dose group

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However, they also appear to affect the neural circuits involved in reward and craving