glutathione withdrawal Figure 15 from Bioactivation of drugs: risk and drug design glutathione withdrawal symptoms peroxidase-1 and

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Consequently, even high-dose GIP infusions have demonstrated minimal glucose-lowering effects in this population [22]

308,309 EMT, CSCs, and DTPs are interconnected via regulatory networks involving transcription factors (e.g., SNAIL, ZEB1), 318 signaling cascades (e.g., TGF-), and cues from the TME (e.g., CAFs, hypoxia), collectively sustaining tumor heterogeneity and adaptive resistance