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The FDA recently approved one of these, elamipretide, for the treatment of a rare genetic mitochondrial disorder

*Correspondence: Hang Lin, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Tissue Engineering and Regenerative Medicine, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

A 20 mg total vial gives about 40 draws at 0.5 mg, 20 draws at 1 mg, or 10 draws at 2 mg

As a result, oxidative stress and tissue damage can occur

doi: 10.1038/s41598-022-10615-z 11 AthinarayananJ.PeriasamyV