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If that holds up in prospective studies, it changes how we think about this disease entirely, and this finding provides a strong rationale for further mechanistic and clinical studies focused on endometrial cancer prevention and treatment. The most dramatic drops in risk, where this reduction was by 50% or more, also occurred in multiple myeloma, pancreatic cancer, and colorectal cancer, in addition to endometrial cancer
However, 30%-40% of tumors treated with tamoxifen develop resistance
Read the full review Nutrition & Metabolic Deficiencies and metabolic drivers of cognitive symptoms
Beyond weight loss, semaglutide improved a broad range of cardiometabolic parameters in ESSENCE [7] , consistent with prior data in T2DM and obesity [10,12]
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