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The FDA has repeatedly warned about dosing errors and safety issues with compounded semaglutide and tirzepatide, including hospitalizations
- Store at room temperature and avoid direct sunlight
[53] Substitutions are made at GLP positions 8 and 34 (semaglutide positions 2 and 28), where alanine and lysine are replaced by 2-aminoisobutyric acid and arginine, respectively
In 2023, as GLP-1s were becoming increasingly used for weight loss, the FDA turned their attention to several other less-common peptides
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