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Seafood Seafood is also a great source of L-Arginine
The replacement of Ala8 with Aib did not significantly change the binding affinity, but did result in a decline in potency as a substrate for DPP4
We propose that in the absence of a peptide, the ECD is dynamic but favors a closed conformation stabilized by the weak interactions between the ECD and ECL1/3
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