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Given that fluoropyrimidine-based therapy will remain a major treatment modality for patients with advanced CRC for the foreseeable future, the need for better, more effective chemotherapy combinations in biologically selected populations to overcome drug resistance is an urgent, unmet need for patients with CRC worldwide

Dosage Protocols Units assume a 50 mg vial in 2 mL of bacteriostatic water (25 mg/mL), so 1 unit = 0.25 mg

Newer drugs target more than one metabolic receptor, which may produce greater effects on weight and blood sugar

Both compounds have demonstrated significant biological activity in experimental models and have begun to attract attention from healthcare professionals seeking novel therapeutic modalities

doi:10.1161/STROKEAHA.122.038640 Heinz J, Kropf S, Domrose U, et al