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The licensing of oral semaglutide was an important therapeutic advance offering an alternative to injectable GLP-1 RAs
Eight patients in the metformin group discontinued the study prematurely: 1 patient due to dyspepsia, 2 due to fatigue, 2 due to a lack of perceived efficacy, 2 due to worsening psychiatric symptoms and a consequent change of psychotropic medication, and 1 due to substance abuse
Thats no small feat, especially considering that people with diabetes often lose less weight than those without
Common Initial Experiences Gastrointestinal symptoms are the most frequently reported side effects
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