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Factors that affect thigh absorption Subcutaneous fat thickness: Thicker fat layers generally mean slower absorption because the medication has more tissue to diffuse through before reaching blood vessels
Unfortunately, prolonged damage to myelin is often irreversible
More specialised tests such as active B12 (holotranscobalamin) or methylmalonic acid may be available through specialist referral, though availability varies across the UK
You are an older adult: Stomach acid production tends to decline with age, which can make it harder to absorb B12 from food and raises the risk of deficiency
This might make it less effective or increase side effects
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