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Because theyre smaller, they can often be absorbed more easily and can connect with very specific spots (receptors) and pathways in your body

6 Beyond the cancer cell itself, the tumor microenvironment (TME), comprising immune cells, stromal components, and extracellular matrix, plays a pivotal role in shaping therapeutic outcomes by fostering immune evasion, altering drug availability, and facilitating cellular crosstalk that promotes resistance

Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine

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F.et al (2019)