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Higher body weight increases skin friction and inflammation, both of which can trigger or worsen HS symptoms
Multivariate linear regression analyses will be used to adjust for weight loss in relation to the variables shown to be statistically significantly associated in the univariate analysis
The pyroptotic process is typically initiated by recognition of pathogens in the cytosol or endogenous danger signals via inflammasomes, which recruit and activate inflammatory caspases such as caspase-1, -4, -5, -11 (160, 161)
7.5mg dose 10mg dose 12.5mg dose 15mg dose (maximum) These quick-reference tables complement the full concentration charts above
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