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as a consequence of increased FAO, tumor-infiltrating DCs differentiate toward a tolerogenic phenotype (tolDCs), with low antigen-presenting capacity and poor T cell priming ( We pause here to acknowledge the unique and important context of the TME, where multiple and often simultaneous challenges and changes impact the subsequent ability of immune cells to elicit potent anti-tumor responses

GLP-1 exerts its anorectic effect in part by acting on the hunger-satiety centre located in the arcuate nucleus of the hypothalamus, and in part by delaying gastric emptying

(Aesthetics Journal, May 29, 2026) That sounds like a green light

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