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The dual approach addressed the pathway at multiple points, producing far superior results than either intervention alone
Chu J, Gallos I, Tobias A, et al
Sen, D., Rosenstein E
To understand if acetylation of Rheb at K151 has any role in GDP release from Rheb, we performed pulling force simulations to investigate the GDP binding strength in Rheb WT, Rheb K151acetylated, and mutants (K151R, K151Q)
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