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In orthotopic osteosarcoma models, CBZP demonstrates powerful antitumor effects and establishes long-term immunity against tumor recurrence, accompanied by enhanced dendritic cell maturation and tumor infiltration of CD8+ T lymphocytes (44)
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References Gregory GA, Robinson TI, Linklater SE, Wang F, Colagiuri S, de Beaufort C, Donaghue KC, Harding JL, Wander PL, ZhangX, Li X
Loss of GSH synthesis induces transcription of NRF2 target genes and repression of lipogenic genes GSH synthesis is required for numerous enzymatic processes across a range of cell types in the body
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