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Fats can take longer to digest, which can make side effects worse, or make you feel too full for too long
Back Unger, RH, Ketterer, H Dupr, J, Eisentraut, I (1967) 'The effects of secretin, pancreozymin, and gastrin on insulin and glucagon secretion in anesthetized dogs', Journal Clinical Investigation , 46/4, 63045
Key takeaways : narrow absorption window drugs, molecules with solubility-limited absorption, and therapies that need rapid onset plus sustained exposure
Therefore, interventions which improve diabetes and weight loss alongside minimising risks and associated morbidity are of interest
Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: rationale and design of the TRIUMPH registrational clinical trials
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