For a broader view of the available study results, our retatrutide clinical trials update covers the most important findings and why the Phase 3 program matters so much
The key milestones include: exenatide approval (2005), liraglutide approval (2010), semaglutide injection approval (2017), oral semaglutide with SNAC approval (2019), orforglipron cryo-EM structure published (2020), orforglipron Phase 2 results in NEJM (2023), orforglipron Phase 3 ATTAIN-1 results in NEJM (2025), and FDA regulatory submission (2025)
Maybe five or six times a day, youre eating something little, but you want it to be balanced, Cahoon said, with a protein, a fruit or vegetable, and whole grain starch or similar
The term GLP-1 refers to the hormone glucagon-like peptide-1, which is naturally produced in the gut after meals and helps regulate appetite, digestion, and insulin release
It can be hard to know which of the hundreds of diets and retail weight loss plans to try