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Evidence from preclinical and clinical studies suggests heterogeneous effects of GLP1RAs on cancer risk: the incidence of hepatocellular, oesophageal, endometrial, ovarian and prostate cancers might be reduced, whereas safety concerns persist with respect to thyroid (both medullary and non-medullary) carcinomas

The full investigation by Sara Talpos, is available at statnews.com

CrossRef Gadoxetate-enhanced MRI Transitional Phase Parenchymal Signal: Effect on Washout and LI-RADS Diagnostic Performance for Hepatocellular Carcinoma Seong Hyeon Cho, Yong Jun Jung, Seung Baek Hong, Se Jin Choi, Seung Soo Lee, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin, Subin Heo, Sang Hyun Choi Radiology .2026;[Epub] CrossRef Hepatocellular carcinoma: current aspects of multidisciplinary management

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This chronological summary highlights major historical milestones from the incretin concept through to the current generation of GLP-1-based therapies and their impacts