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Very common side effects feeling sick (nausea) diarrhoea vomiting constipation low blood sugar (if used with certain diabetes medications) Common side effects indigestion stomach pain dizziness allergic reactions low blood pressure hair loss feeling tired bloating burping gas reflux or heartburn injection site reactions an increased level of some pancreatic enzymes as shown in blood tests (such as lipase) increased calcitonin levels Uncommon side effects gallstones fast pulse injection site pain gall bladder infection (cholecystitis) inflammation of the pancreas an increased level of some pancreatic enzymes as shown in blood tests (such as amylase) increased calcitonin levels in blood change in sense of taste skin sensation changes delay in stomach emptying For a full list of the side effects see the Patient Information Leaflet
A STAT News investigation highlighted that microdosing aims to extend the lifespan of the GLP-1 compounding market, with physicians and researchers noting there is no clinical evidence that tirzepatide is effective at very small doses
But right now, unfortunately, it is unsustainable. The states biggest private insurer, Blue Cross Blue Shield of Massachusetts, also axed coverage of GLP-1 drugs for weight loss this year because the costs were driving up premiums for all members
Are semaglutide and tirzepatide safe
If you do not see a significant difference with Wegovy or experience side effects, switching to Zepbound may provide better tolerance and more significant weight loss results
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